What is new in the treatment of peripheral T-cell lymphomas

Abstract

Peripheral T-cell lymphomas (PTCL) belong to a group of Non-Hodgkin's lymphomas, characterized by considerable heterogeneity and, compared to B-lymphomas, by poorer treatment response, limited treatment options, and high mortality. Statistical data concerning patients with PTCL, including those collected in the Czech Republic, clearly point to the necessity of searching for new strategies to improve the prognosis of patients with PTCL. The heterogeneity of T-lymphomas and the lack of understanding of their pathogenesis have caused inaccurate and imperfect diagnoses and insufficient development of targeted and effective treatment procedures.