How do anti-SARS-CoV-2 IgG and IgM predict the titre of virus-neutralizing antibodies in donors of convalescent plasma against covid-19 disease?

Abstract

Convalescent plasma was one of the treatment modalities in patients with severe or moderate course of the new acute respiratory disease covid-19. The basic condition for its administration is a sufficient virus neutralizing antibody titre ≥160. The aim of the present study is the analysis of the data of convalescent anti-covid plasma donors of the Transfusion Department of the Olomouc University Hospital, assessment of the correlation between individual examined parameters and their evaluation in relation to the recommendation of the treatment with convalescent plasma in adult patients with covid-19.