Cryopreservation of ovarian tissue as a method for fertility preservation in women

Abstract

Objective: To summarize the current possibilities of ovarian tissue cryopreservation as one of the other possible methods for fertility preservation in women

Design: Review article

Setting: Department of Obstetrics and Gynecology, University Hospital Olomouc, Faculty of Medicine, Palacky University in Olomouc

Methods: Literature review of studies and literature works to ovarian tissue cryopreservation

Conclusion: Cryopreservation of ovarian tissue and its subsequent transplantation have a significant potential for preserving fertility not only for prepubertal and oncological patients, but also for patients with various medical indications leading to premature ovarian insufficiency. In order to maintain the best possible quality of oocytes in cryopreserved ovarian tissue, it is necessary to constantly optimize, standardize and compare both cryopreservation protocols, procedures and strategies, as well as the process of thawing ovarian tissue with its subsequent transplantation.

Keywords: fertility preservation, cryopreservation of ovarian tissue, slow freezing, vitrification, oncofertility, assisted reproduction, in vitro fertilization, in vitro maturation