Srovnání využití dinoprostonu, misoprostolu a amniotomie při indukci vaginálního porodu: prospektivní observační studie Comparison of dinoprostone, misoprostol and amniotomy in labor induction: Prospective observational study

Abstract

ABSTRACT

Objective: Comparison of dinoprostone, misoprostol and amniotomy in labor induction.  

Design: Prospective observational study.

Setting: Department of Obstetrics and Gynecology, University Hospital, Palacky University, Olomouc.

Methods: The study group included a total of 437 women who underwent consecutive induction of labor after evaluation of the indication and Bishop´s score. The most common indications were: postmaturity, hypertensive disease, diabetes mellitus and fetal growth restriction. In 327 cases we chose to induce labor using vaginal tabletes of dinoprostone in dose 0.75 mg, in 36 cases dinoprostone in dose 3 mg, in 16 cases we used vaginal insert of misoprostol 200 ug and in 58 cases amniotomy was performed. Results: In the subgroup of dinoprostone 0,75 mg the rate of vaginal delivery (including of extraction delivery) was 90.2 %, in subgroup of dinoprostone 3 mg it was 91.6%, in subgroup of misoprostol it was 100% and in subgroup of amniotomy it was 93.1%.The time period between onset of labor induction and delivery was average 15.75 hours in dinoprostone 0.75 mg subgroup, 21.41 hours in dinoprostone 3 mg subgroup, 17.41 hours in misoprostol subgroup and 7.49 hours in amniotomy subgroup. Conclusion: Subgroup of patients with misoprostol has shown the highest rate of vaginal delivery after labor induction. In subgroup with amniotomy the shortest time period between onset of induction and delivery was reached. 

KEYWORDS

Bishop score, induction of labor, predictive factors