Update on treatment of mycosis fungoides and Sézary syndrome

Abstract

The aim of this review article is to introduce the readers to the topic of cutaneous T-cell lymphomas - mycosis fungoides and Sézary syndrome and the current treatment options. Cutaneous T-cell lymphomas are a rare group of non-Hodgkin's lymphomas. Mycosis fungoides and Sézary syndrome are the most common subtypes of cutaneous T-cell lymphomas. Advanced stages of mycosis fungoides and Sézary syndrome are burdened by significant morbidity and mortality and limited therapeutic options. Mogamulizumab represents a new effective systemic therapy for patients with mycosis fungoides and Sézary syndrome.